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Sci Rep ; 5: 10884, 2015 Jun 03.
Artigo em Inglês | MEDLINE | ID: mdl-26039461

RESUMO

Dental hypersensitivity due to exposure of dentinal tubules under the enamel layer to saliva is a very popular and highly elusive technology priority in dentistry. Blocking water flow within exposed dentinal tubules is a key principle for curing dental hypersensitivity. Some salts used in "at home" solutions remineralize the tubules inside by concentrating saliva ingredients. An "in-office" option of applying dense resin sealants on the tubule entrance has only localized effects on well-defined sore spots. We report a self-assembled film that was formed by facile, rapid (4 min), and efficient (approximately 0.5 g/L concentration) dip-coating of teeth in an aqueous solution containing a tannic acid-iron(III) complex. It quickly and effectively occluded the dentinal tubules of human teeth. It withstood intense tooth brushing and induced hydroxyapatite remineralisation within the dentinal tubules. This strategy holds great promise for future applications as an effective and user-friendly desensitizer for managing dental hypersensitivity.


Assuntos
Sensibilidade da Dentina/tratamento farmacológico , Ferro , Soluções Farmacêuticas/administração & dosagem , Taninos , Técnicas de Cultura de Células , Líquido Dentinal/metabolismo , Humanos , Ferro/química , Ligamento Periodontal/citologia , Soluções Farmacêuticas/química , Taninos/química , Dente/efeitos dos fármacos
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